Kirsner炎症性肠疾病

书籍目录

List of ContributorsForewordPrefaceSection I　Mucosal protection and homeostasis　1.Intestinal epithelia barrier function: characteristics and responses to neutrophil transepithelial migration　2.Epithelial restitution and intestinal repair　3.Epithelial-microbial interactions　4.Immune cell-epithelial cell interactions　5.The regulation of mucosal homeostasis and its relation to inflammatory bowel diseases　6.T-lymphocyte trafficking　7.Leukocyte, platelet and endothelial cell interactions in the inflammatory bowel diseasesSection II　Etiology and pathogenesis　8.Genetics: molecular and chromosomal considerations　9.Animal models of intestinal inflammation　10.Microbial influences in inflammatory bowel diseases: role in pathogenesis and clinical implications　11.Mechanisms of tissue injury　12.Cytokines and inflammatory mediators　13.T-lymphocyte dysregulation　14.Neuroimmune interactions in the inflamed intestine　15.Fibrogenesis　16.Colorectal cancer in inflammatory bowel disease:molecular considerationsSection III　Epidemiology, clinical features and natural history　17.Epidemiology of inflammatory bowel diseases　18.Clinical genetics of inflammatory bowel diseases:genetic epidemiology, genotype-phenotype correlations and pharmacogenetics　19.Clinical course and natural history of ulcerative colitis　20.Clinical features and natural history of Crohn's disease　21.Clinical features and natural history of pediatric inflammatory bowel diseases　22.Physiologic consequences of surgical treatment for inflammatory bowel disease　23.Fertility and pregnancy　24.Psychosocial factors in ulcerative colitis and Crohn's diseaseSection IV  Diagnosis and evaluationSection V  Medical therapySection VI  Surgical therapySection VII  Complications and associated diseasesIndex

作者简介

　　This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial teamjoined by a superb group of international authoritiesexamine every aspect of IBDincluding etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource.　　Emphasizes evidence-based medicine in the section on medical therapy.　　Features a detailed description of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD.　　Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics.　　Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographsplacing the various diagnostic modalities in perspective. 　　Offers extensive coverage of postoperative recurrence of Crohn's disease 　　· pouchitis 　　· microscopic colitis 　　· perianal disease 　　· and osteoporosis. 　　Includes up-to-the-minute guidance (including many 2003 references). 　　Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives.　　Includes nine new chapters.　　Offers expanded coverage throughout, and through revisions of all pre-existing chapters.　　With over 75 additional contributing experts.

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