诊断微生物学

书籍目录

PART Ⅰ INTRODUCTION TO CLINICAL MICROBIOLOGY　1 Bacterial Cell StructurePhysiologyMetabolismand Genetics　　Significance    Overview of the Microbial World    Classification/Taxonomy    Comparison of Eukaryotic and Prokaryotic Cell Structure    Bacterial Morphology    Microbial Growth and Nutrition    Bacterial Biochemistry and Metabolism    Bacterial Genetics  2 Host-Pathogen Interaction    A. The Role of the Usual Microbial Flora      Origin of Microbial Flora      Composition of the Microbial Flora at Different Body Sites      Role of the Microbial Flora in the Pathogenesis of Infectious Disease      Role of the Microbial Flora in the Host Defense against Infectious Disease    B. Pathogenesis of Infection      Microbial Factors Contributing to Pathogenesis and Virulence      Host Resistance Factors      Mechanisms by which Microbes May Overcome the Host Defenses Routes of Transmission  3 The Laboratory Role in Infection Control    General Concepts in Infection Control Practice    Outbreak Investigation    Education    Emerging and Reemerging Pathogens  4 Control of Microorganisms    A. Disinfection and Sterilization      Sterilization versus Disinfection      Factors That Influence the Degree of Killing      Methods of Disinfection and Sterilization      Disinfectants versus Antiseptics      EPA Regulations on Chemical Surface Disinfectants      FDA Regulations on Chemical Skin Antiseptics    B. Microbiology Safety      General Microbiology Safety      Bioterrorism and the Clinical Microbiology Laboratory  5 Performance improvement in the Microbiology Laboratory    A. Quality Issues in Clinical Microbiology      General Guidelines for Establishing Quality Control Performance Improvement    B. Putting the Laboratory Test to the Test      Analytical Analysis of Tests      Clinical Analysis of Tests      Operational Analysis of Tests      Choosing a Laboratory Method      Test Validation  6 Specimen Collection and Processing    Basic Principles of Specimen Collection    PreservationStorageand Transport of Specimens    Specimen Receipt and Processing    Culture Workup    Nonroutine Specimens    Communication of Laboratory Findings  7 Microscopic Examination of Infected Materials    Preparation of Samples    Stains    Microscopes    Terminology for Direct Examinations    Examination of Prepared Material    Grading or Classifying Materials    Reports of Direct Examinations    Examples of Sample Observations and Reports    Quality Control in Direct Microscopic Interpretations  8 Use of Colonial Morphology for the Presumptive Identification of Microorganisms    Importance of Colonial Morphology as a Diagnostic Tool    Initial Observation and Interpretation of Cultures    Gross Colony Characteristics Used to Differentiate and Presumptively Identify Microorganisms    Colonies with Multiple Characteristics    Growth of Organisms in Liquid Media　……PART Ⅱ LABORATORY IDENTIFICATION OF SIGNIFICANT ISOLATESPART Ⅲ LABORATORY OIAGNOSIS OF INFECTIOUS: AN ORGAN SYSTEM APPROACHAPPENDIXES

作者简介

Completely updated and in full color, this 3rd edition covers all the essentials of diagnostic microbiology. A logical building-block approach supplies what students need to know in an easy-to-use, memorable format. Material is presented in a progressive manner, from basic principles and concepts to systematic identification of etiologic agents of infectious diseases, promoting greater understanding and the development of problem-solving skills. Part I of the text explains basic principles and concepts, setting up a firm foundation in microbiology. Building on these basics, Part II highlights methods for the identification of significant isolates. Part III uses an organ system approach to discuss the laboratory diagnosis of infectious diseases with a focus on the most medically significant and commonly encountered diseases.    More than 800 full-color illustrations.　　Hands-on procedures describe laboratory techniques.　　A case study begins each chapter with a related, real-life situation.　　All chapters make learning easier with features such as outlines, objectives, key terms, chapter summaries, points to remember, and learning assessment questions.　　Five new chapters:　　The Laboratory Role in Infection Control　　Biochemical Identification of Gram-Negative Bacteria　　Immunodiagnosis of Infectious Diseases　　Agents of Bioterror　　Biofilms: Architects of Disease　　Antimicrobial Susceptibility Testing chapter has been expanded to include emerging microbial resistance and pharmacokinetic and pharmacodynamic principles and applications.　　Issues to Consider encourages critical thinking and analysis of featured case studies.Glossary of terms serves as a quick reference.　　New co-editor, Don Lehman, brings years of educational experience.

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